Targeting hope

DNA methylation markers to predict
treatment succes of biologicals in Crohn’s
disease, rheumatoid arthritis and psoriasis

About METHYLOMIC

METHYLOMIC is committed to bringing personalised treatment-selection in Crohn’s disease and other immune-mediated inflammatory diseases to clinical practice.

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Duration

4 Years

Budget

10 Million

18 partners

9 countries

Why METHYLOMIC?

Crohn's disease

The prime purpose of METHYLOMIC is to develop and clinically validate a novel epigenetic biomarker tool that enables the identification of most optimal treatments for individual patients and hence to ensure an effective and efficient use of existing and broadly prescribed biologicals for Crohn´s disease (CD).

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Rheumatoid Arthritis

The EPIPSORA trial will be carried out as part of the METHYLOMIC project. This study will investigate whether it is possible to develop and validate an epigenetic biomarker that predicts treatment success for rheumatoid arthritis (RA).

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Psoriasis

The EPIPSORA trial will be carried out as part of the METHYLOMIC project. This study will investigate whether it is possible to develop and validate an epigenetic biomarker that predicts treatment success for psoriasis (PsO).

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