WP1: Bioinformatics and algorithm development
The main aim of this WP is to generate, improve and refine the algorithms capable of predicting response to biological treatment based on epigenetic DNA methylation markers that we found to discriminate responders from non-responders to treatment with 3 different mainstream biologicals in CD. Further, we also test the validity of this approach in Rheumatoid Arthritis (RA) and Psoriasis (PsO).