This video offers a closer look at the work of the Horizon Europe project METHYLOMIC, of which IFCCA is a participating member. With contributions from gastroenterologists Dr Peter Bossuyt and Dr Virginia Solitano, as well as patient representative Marieke Oosting, the video highlights the transformative potential of predictive biomarkers in the development of more effective and truly personalised treatments.
Advancing Personalised Care with METHYLOMIC
Documentary: The Search for Better Biomarkers in IBD
Inside the OmiCrohn Study
Documentary: Epigenetics and the future of IBD care
This video offers an introduction to the OMICROHN Study, developed within the Horizon Europe project METHYLOMIC, in which IFCCA is a participating member. With contributions from Prof. Jack Satsangi, Dr Alexandra Noble, Prof. Geert D’Haens, and patient representative Marieke Oosting, the video explores how epigenetics and DNA methylation could support a more personalised and forward-looking approach to inflammatory bowel disease care.
Podcast METHYLOMIC Matters - EFCCA and OmiCrohn
In this episode, EFCCA Innovation and Patient Engagement Coordinator Roberto Saldaña and EFCCA CEO Luisa Avedano share their views on the OmiCrohn clinical trial and reflect on the potential impact it may have on the lives of people living with Crohn’s disease.
Methylomic Matters is a podcastseries by the METHYLOMIC project: a program committed to bringing personalised treatment-selection in Crohn’s disease and other immune-mediated inflammatory diseases to clinical practice.
Podcast METHYLOMIC Matters - About Epipsora
This episode, especially aimed at patients with Rheumatoid Arthritis, features Marleen van de Sande, rheumatologist at Amsterdam UMC, and Frank van Empel, a patient with RA. The episode explores the Episora trial, a major study that uses AI to help determine which medication is most effective for each patient, offering a more efficient alternative to the current trial-and-error approach.
Methylomic Matters is a podcastseries by the METHYLOMIC project: a program committed to bringing personalised treatment-selection in Crohn’s disease and other immune-mediated inflammatory diseases to clinical practice.
Podcast METHYLOMIC Matters - About OmiCrohn
In this episode, journalist Shula Tas interviews Prof. Geert D’Haens (Amsterdam UMC) and Marjolijn Duijvestein (Radboudumc) and Dalia de Jong who has Crohn’s Disease.
This episode focuses on current treatments for Crohn’s disease and the potential relevance of the OmiCrohn trial for patients.
Methylomic Matters is a podcastseries by the METHYLOMIC project: a program committed to bringing personalised treatment-selection in Crohn’s disease and other immune-mediated inflammatory diseases to clinical practice.
Podcast METHYLOMIC Matters - About OmiCrohn and Epipsora
In this episode, journalist Shula Tas interviews Prof. Geert D’Haens about how methylation research aims to improve treatment selection for Crohn’s disease, Rheumatoid Arthritis and Psoriasis through personalized medicine.
Methylomic Matters is a podcastseries by the METHYLOMIC project: a program committed to bringing personalised treatment-selection in Crohn’s disease and other immune-mediated inflammatory diseases to clinical practice.
Podcast METHYLOMIC Matters - Omicrohn's Rapid Assay Development
Methylomic Matters is a podcastseries by the METHYLOMIC project: a program committed to bringing personalised treatment-selection in Crohn’s disease and other immune-mediated inflammatory diseases to clinical practice. In this podcastseries our host Dr. Vincent Joustra discusses several topics on DNA-methylation, machine based learning and how to bring these techniques to clinical practice.
In the fourth episode of METHYLOMIC matters our attention centers on a crucial element of METHYLOMIC: the development of an easy-to-use diagnostic test intended for clinical validation, with the ultimate aim of global adoption in medical centers. With Dr. Peter Henneman and Dr. Jules Petit we discuss the importance of a rapid assay and compare its pros and cons opposed to the current EPIC array methodology. All this and more in the fourth episode of METHYLOMIC matters!
Listen to the podcast
You can listen to the METHYLOMIC podcast through one of the below podcast channels:
Podcast METHYLOMIC Matters - Machine Learning Magic Behind the Treatment Response
Methylomic Matters is a podcastseries by the METHYLOMIC project: a program committed to bringing personalised treatment-selection in Crohn’s disease and other immune-mediated inflammatory diseases to clinical practice. In this podcastseries our host Dr. Vincent Joustra discusses several topics on DNA-methylation, machine based learning and how to bring these techniques to clinical practice.
In the third episode of METHYLOMIC matters we delve into the intricate machine learning methodology behind the successful prediction models developed by HORAIZON’s founder and CEO, dr. Evgeni Levin. We explore essential elements of the methodology, comparing linear and non-linear models, emphasizing the significance of multivariate models, and addressing strategies for mitigating overfitting. Furthermore, we delve into the prospective clinical applications of these models and their ultimate integration into clinical practice. All this and more in the third episode of METHYLOMIC matters!
Listen to the podcast
You can listen to the METHYLOMIC podcast through one of the below podcast channels:
Podcast METHYLOMIC Matters - Results from the EPIC-CD project
Methylomic Matters is a podcastseries by the METHYLOMIC project: a program committed to bringing personalised treatment-selection in Crohn’s disease and other immune-mediated inflammatory diseases to clinical practice. In this podcastseries our host Dr. Vincent Joustra discusses several topics on DNA-methylation, machine based learning and how to bring these techniques to clinical practice.
In the second episode of METHYLOMIC matters we have the privilege of conversing with Professor Geert D’Haens and Dr. Andrew Li Yim as we delve into the pre-METHYLOMIC era and discover the science behind the OMICROHN trial: the EPIC-CD study. How did we design this biomarker discovery study and what are key important methodological steps? What were the main results and how do we envision the future? All this and more in the second episode of METHYLOMIC matters!
Listen to the podcast
You can listen to the METHYLOMIC podcast through one of the below podcast channels:
Podcast METHYLOMIC Matters - The concept of DNA methylation in Inflammatory Bowel Disease
Methylomic Matters is a podcastseries by the METHYLOMIC project: a program committed to bringing personalised treatment-selection in Crohn’s disease and other immune-mediated inflammatory diseases to clinical practice. In this podcastseries our host Dr. Vincent Joustra discusses several topics on DNA-methylation, machine based learning and how to bring these techniques to clinical practice.
In the first episode of METHYLOMIC matters we will speak with dr. Anje te Velde and Professor Wouter de Jonge, diving into the concept of DNA methylation changes in IBD and their potential to be used as biomarkers of therapy response in IBD. What is epigenetics and how does it work? Why is DNA methylation interesting in complex immune mediated diseases and what is the history behind the EPIC-CD and METHYLOMIC projects? All this and more in the first episode of METHYLOMIC matters!
Listen to the podcast
You can listen to the METHYLOMIC podcast through one of the below podcast channels: